Skeletal muscle fibres secreting myokine proteins — represented in gold — into the bloodstream, where they travel to reach a hippocampal neuron. The illustration depicts the muscle-to-brain signalling pathway at the centre of Cathepsin B research.

The Outside-In Protocol

Self portrait of Henriette van Praag, Associate Professor at Florida Atlantic University’s Stiles-Nicholson Brain Institute and Charles E. Schmidt College of Medicine. Image credit: Henriette van Praag How a protein released by exercising muscle may hold the key to protecting the aging brain — without touching a single amyloid plaque Editor’s Note For nearly a […]

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